SamE = fat and happy?

David Cohen wrote:

> "JMW" <jmwilliams_56.DeleteThis@yahoo.com> wrote
>
>>David Cohen wrote:
>>
>>>Allow me to add my cheap Jew comment at this point: SAMe is freakin'
>>>expensive!!
>>
>>But it does have a half-decent and enduring stimulant effect in
>>combination with some other natural substrates and xenobiotics, correct?
>
>
> Yes.
>
> And it's freakin' expensive!

My family & neighbors started up a collection to get me on it.

HTH

Dally
 >> Stay informed about: SamE = fat and happy? 

On Wed, 28 Dec 2005 18:09:12 -0500, WillBrink
<WillBrink*NOSPAM*@Comcast.net> wrote:

>In article <17633.DeleteThis@134412590.57419254.11577.6155.20901>,
> DZ <9456.DeleteThis@2196910326.230324815.18363.11851.13323.com> wrote:
>
>> WillBrink wrote:
>> > JMW <jmw.DeleteThis@event.horizon> wrote:
>> >> WillBrink wrote:
>> >> > DZ wrote:
>> >>>> Can you post the summary here? I know that SAMe needs to be taken
>> >>>> with B vitamins to protect from the increase of
>> >>>> homocysteine. Anything else?
>> >>
>> >>>I didn't know SAMe raised homocysteine. Is it not also a methyl
>> >>>donor(?), which in theory, should lower homocysteine.
>> >>>
>> >>> Giulidori P, Galli-Kienle M, Catto E, Stramentinoli G.
>> >>> Transmethylation, transsulfuration, and aminopropylation
>> >>> reactions of S- adenosyl-L-methionine in vivo. J Biol Chem
>> >>> 1984;259:4205-11
>> >>
>> >> No elevation of homocysteine in fifteen test subjects at 1600mg/day of
>> >> SAMe.
>> >
>> > As a methyl donor, I would have expected to see a drop in homocysteine
>> > as you do with other methyl donors.
>>
>> The effect can be opposite if they are a part of the methionine cycle
>> (methionine -> SAMe -> SAH <-> homocysteine -> back to
>> methionine). For example, it would make sense that methionine, which
>> is also a methyl donor, would raise homocysteine. But those methyl
>> donors that speed up re-methylation of homocysteine back to methionine
>> can reduce its concentration.
>
>As John pointed out, it does not appear to increase homocysteine. I was
>under the impression it lowered it, but perhaps it has no effects either
>way. Have not looked into it much.
>
>>
>> So, I have some vague interest in SAMe but I'm undecided on pros and
>> cons. There is some evidence that methionine reduces lifespan.
>
>Are there any SAMe life span studies in animals perhaps?

Why even bother with SamE when you can get far more bang for your buck
with Ketamine:

http://www.health.org/nongovpubs/ketamine/

This is for peoples and animals so it's the way to go folks. ;o)

HTH
 >> Stay informed about: SamE = fat and happy? 

In article <IMFsf.10583$3Z.3928@newsread1.news.atl.earthlink.net>,
"David Cohen" <sammiesdad RemoveThis @earthlink.net> wrote:

> Allow me to add my cheap Jew comment at this point: SAMe is freakin'
> expensive!!

That much I know.

>
> David
>
>

--
Will Brink @ http://www.brinkzone.com/
 >> Stay informed about: SamE = fat and happy?