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More use of arachidonic acid in bodybuilding

 
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Taka

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Since: Jan 02, 2008
Posts: 10



(Msg. 1) Posted: Sat Jul 19, 2008 12:04 am
Post subject: More use of arachidonic acid in bodybuilding
Archived from groups: sci>life-extension, others (more info?)

The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
stimulate nitric oxide synthase while supplementing it with enough
substrate in the form of Arginine. IMHO this formula should also work
for great erections ...

From the full text at http://www.myonet.com/p-AX12.htm :

"Nitric Oxide is a byproduct of Arginine being broken down in the body
by an enzyme called Nitric Oxide Synthase (NOS). Your body only has a
limited supply of NOS. Consequently, no matter how much Arginine you
have flooded your system with, your NO will only be as high as the
amount of NOS you have to break it down. We have a breakthrough way to
create more of the key enzyme, NOS. The result…RIDICULOUS PUMPS! We
are talking pumps so big, they almost hurt. Excited yet?

How in the heck to did you do this? You might ask. The answer is the
addition of a compound called Arachidonic Acid (AA). You may have seen
AA in other products because it has so many benefits. But you have
never seen it used this way before. AA has the ability to turn on
(upregulate) NOS through a complex process. Once AA is released from
the phospholipid layer of each muscle cell during exercise, it is
rapidly converted to prostaglandins (PGE2). PGE2 upregulates the
enzyme NOS creating the perfect environment for MASS Nitric Oxide
production."

"Arachidonic Acid
HemodrauliX is the first nitric oxide product ever to harness the
power of Arachidonic Acid (AA). The powerful combo of AA and NO work
together to ignite a cascading process that leads to pumps and
endurance never before experienced by the bodybuilding and athletic
world. Arachidonic Acid is the precursor to cell-signaling molecules
called prostaglandins (PGE2). In addition to being highly anabolic,
PGE2 works with Nitric Oxide to create massive vasodialation, feeding
the muscles by increasing blood flow, oxygen and assisting with
glucose uptake. You’ve heard supplement companies promise skin-
bursting pumps before. Now it’s time to actually experience them."


It seems to me that one way to suppress the production of the bad
destructive AA metabolites called leukotrienes is to involve in
resistance exercise. Could it be the excessive carbohydrates
(particularly fructose) not burned for energy which stimulate the bad
guys like LTB4??

Taka

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Kofi

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Since: Jul 19, 2008
Posts: 2



(Msg. 2) Posted: Sat Jul 19, 2008 1:22 pm
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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In article
,
Taka wrote:

> This invention discloses a method of orally administering arachidonic
> acid for the purpose of increasing the serum level of the
> prostaglandin PGF2alpha and subsequently the level of retained
> skeletal muscle mass.

FYI, FGF2a stimulates IL-6 [PMID 11968002] - so you could have a guy who
has muscle wasting because he has Crohn's disease and too much IL-6 and
I bet some joker somewhere will read this patent and then try giving the
guy arachidonic acid.

Doh!

(You're also going to stimulate the development of colon cancer this
way.)

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Kofi

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Since: Jul 19, 2008
Posts: 2



(Msg. 3) Posted: Sat Jul 19, 2008 1:26 pm
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
Archived from groups: per prev. post (more info?)

In article
,
Taka wrote:

> The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
> stimulate nitric oxide synthase while supplementing it with enough
> substrate in the form of Arginine. IMHO this formula should also work
> for great erections ...
>
> From the full text at http://www.myonet.com/p-AX12.htm :
>
> "Nitric Oxide is a byproduct of Arginine being broken down in the body
> by an enzyme called Nitric Oxide Synthase (NOS). Your body only has a
> limited supply of NOS. Consequently, no matter how much Arginine you
> have flooded your system with, your NO will only be as high as the
> amount of NOS you have to break it down. We have a breakthrough way to
> create more of the key enzyme, NOS. The resultŠRIDICULOUS PUMPS! We
> are talking pumps so big, they almost hurt. Excited yet?
>
> How in the heck to did you do this? You might ask. The answer is the
> addition of a compound called Arachidonic Acid (AA). You may have seen
> AA in other products because it has so many benefits. But you have
> never seen it used this way before. AA has the ability to turn on
> (upregulate) NOS through a complex process. Once AA is released from
> the phospholipid layer of each muscle cell during exercise, it is
> rapidly converted to prostaglandins (PGE2). PGE2 upregulates the
> enzyme NOS creating the perfect environment for MASS Nitric Oxide
> production."
>
> "Arachidonic Acid
> HemodrauliX is the first nitric oxide product ever to harness the
> power of Arachidonic Acid (AA). The powerful combo of AA and NO work
> together to ignite a cascading process that leads to pumps and
> endurance never before experienced by the bodybuilding and athletic
> world. Arachidonic Acid is the precursor to cell-signaling molecules
> called prostaglandins (PGE2). In addition to being highly anabolic,
> PGE2 works with Nitric Oxide to create massive vasodialation, feeding
> the muscles by increasing blood flow, oxygen and assisting with
> glucose uptake. You¹ve heard supplement companies promise skin-
> bursting pumps before. Now it¹s time to actually experience them."
>
>
> It seems to me that one way to suppress the production of the bad
> destructive AA metabolites called leukotrienes is to involve in
> resistance exercise. Could it be the excessive carbohydrates
> (particularly fructose) not burned for energy which stimulate the bad
> guys like LTB4??
>
> Taka

Looking strictly at the pathways, you could also get this effect taking
estrogen - it's an eNOS stimulant - but somehow, I don't think any of
these guys are going to try it. There's also citrulline, folic acid/BH4
and straight superoxide dismutase. Many of them have some real risks to
them (BH4 and Parkinson's, for instance). Frankly, fiddling along this
pathway for a little extra muscle is just plane stupid
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DZ

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Since: Jul 20, 2008
Posts: 1



(Msg. 4) Posted: Sun Jul 20, 2008 4:13 am
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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Taka

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Since: Jan 02, 2008
Posts: 10



(Msg. 5) Posted: Sun Jul 20, 2008 8:48 am
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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On Jul 20, 3:22 am, Kofi wrote:
> In article
> ,
>
> Taka wrote:
> > This invention discloses a method of orally administering arachidonic
> > acid for the purpose of increasing the serum level of the
> > prostaglandin PGF2alpha and subsequently the level of retained
> > skeletal muscle mass.
>
> FYI, FGF2a stimulates IL-6 [PMID 11968002] - so you could have a guy who
> has muscle wasting because he has Crohn's disease and too much IL-6 and
> I bet some joker somewhere will read this patent and then try giving the
> guy arachidonic acid.
>
> Doh!
>
> (You're also going to stimulate the development of colon cancer this
> way.)

It seems to me that the serious bodybuilders could be well depleting
AA in the muscle cells quite efficiently by the strenuous training -
see my previous post entitled "Spaceflight muscle wasting" which shows
how any muscle use produces prostaglandins which are not going to turn
back into AA afterwards. When you reach a plateau in the muscle
growth you don't usually get the usual DOMS (delayed muscle pain/
soreness) anymore. Because DOMS are caused by the very AA metabolites
like PGF2a, PGE2 this may signal that there is not enough AA precursor
probably because not enough delta-5 desaturase is hanging around for
the great demand during intense trainings. So I suspect that in the
trained individuals any supplementary AA would be quickly soaked into
the muscle fibers without causing any systemic inflammatory problems.
Of course on the other hand it can cause a lot of damage to a
sedentary folk on an Omega-6 rich diet whose muscles are already
overloaded with AA to begin with.

Taka
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Taka

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Since: Jan 02, 2008
Posts: 10



(Msg. 6) Posted: Mon Jul 21, 2008 6:02 am
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
Archived from groups: sci>life-extension, others (more info?)

Another related thought is that when the top athletes quit the
training they often start feeling bad due to different inflammatory
problems such as aching joints because their desaturase system has
been conditioned for the high AA demand during intense muscle work and
they start getting excess of it in the absence of the exercise. Same
as the SNPs overactivating the delta-5 desaturase linked to vascular
diseases.

Taka
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Taka

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Since: Jan 02, 2008
Posts: 10



(Msg. 7) Posted: Tue Jul 22, 2008 6:07 am
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
Archived from groups: sci>life-extension, others (more info?)

On Jul 22, 8:25 pm, Tom Anderson wrote:
> On Sat, 19 Jul 2008, Taka wrote:
> > The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
> > stimulate nitric oxide synthase while supplementing it with enough
> > substrate in the form of Arginine. [...] How in the heck to did you do
> > this? You might ask. The answer is the addition of a compound called
> > Arachidonic Acid (AA).
>
> That's in peanuts, right?

No, only its precursor linoleic acid. It is in relatively high
amounts in organ meat such as hearts and egg yolks. Also in recently
mentioned farmed salmon fed grains.

Taka
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Tom Anderson

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Since: May 02, 2006
Posts: 298



(Msg. 8) Posted: Tue Jul 22, 2008 12:25 pm
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
Archived from groups: per prev. post (more info?)

On Sat, 19 Jul 2008, Taka wrote:

> The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
> stimulate nitric oxide synthase while supplementing it with enough
> substrate in the form of Arginine. [...] How in the heck to did you do
> this? You might ask. The answer is the addition of a compound called
> Arachidonic Acid (AA).

That's in peanuts, right?

tom

--
And the evening and the morning were the fifth day.
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Omelet

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Since: May 19, 2008
Posts: 102



(Msg. 9) Posted: Tue Jul 22, 2008 12:25 pm
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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In article ,
Tom Anderson wrote:

> On Sat, 19 Jul 2008, Taka wrote:
>
> > The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
> > stimulate nitric oxide synthase while supplementing it with enough
> > substrate in the form of Arginine. [...] How in the heck to did you do
> > this? You might ask. The answer is the addition of a compound called
> > Arachidonic Acid (AA).
>
> That's in peanuts, right?
>
> tom

Be careful with that. I recall some information on some other compound
in peanuts causing infertility in men.

Don't ask me for a cite. This is a memory dredged up from many moons
ago...
--
Peace! Om

"Human nature seems to be to control other people
until they put their foot down." -- Stephan Rothstein
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Taka

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Since: Jan 02, 2008
Posts: 10



(Msg. 10) Posted: Tue Jul 22, 2008 6:03 pm
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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On Jul 22, 10:07 pm, Taka wrote:
> On Jul 22, 8:25 pm, Tom Anderson wrote:
>
> > On Sat, 19 Jul 2008, Taka wrote:
> > > The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
> > > stimulate nitric oxide synthase while supplementing it with enough
> > > substrate in the form of Arginine. [...] How in the heck to did you do
> > > this? You might ask. The answer is the addition of a compound called
> > > Arachidonic Acid (AA).
>
> > That's in peanuts, right?
>
> No, only its precursor linoleic acid. It is in relatively high
> amounts in organ meat such as hearts and egg yolks. Also in recently
> mentioned farmed salmon fed grains.
>
> Taka

Don't mistake arachidonic for arachidic, the latter is a saturated
fatty acid indeed found in peanut oil:

http://en.wikipedia.org/wiki/Arachidic_acid

Taka
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DZ

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Since: Jul 22, 2008
Posts: 1



(Msg. 11) Posted: Tue Jul 22, 2008 8:05 pm
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DZ

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Since: Jul 23, 2008
Posts: 1



(Msg. 12) Posted: Wed Jul 23, 2008 4:46 am
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Andrzej Rosa

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Since: Oct 29, 2005
Posts: 629



(Msg. 13) Posted: Wed Jul 23, 2008 7:12 am
Post subject: Re: More use of arachidonic acid in bodybuilding [Login to view extended thread Info.]
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DZ wrote:

> Taka wrote:
>> On Jul 22, 8:25 pm, Tom Anderson wrote:
>>> On Sat, 19 Jul 2008, Taka wrote:
>>> > The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
>>> > stimulate nitric oxide synthase while supplementing it with enough
>>> > substrate in the form of Arginine. [...] How in the heck to did you do
>>> > this? You might ask. The answer is the addition of a compound called
>>> > Arachidonic Acid (AA).
>>>
>>> That's in peanuts, right?
>>
>> No, only its precursor linoleic acid. It is in relatively high
>> amounts in organ meat such as hearts and egg yolks. Also in recently
>> mentioned farmed salmon fed grains.
>> Taka
>
> No, Taka, you don't understand.
>
> Tom is one of our musclehead nerd scientists, a biochemist from
> Oxford.

It's so fortunate that you have nothing to do with KGB. It would be such a
shame if your beloved shrimp fed cat got lost due to a security breach in
some totally unrelated but conveniently nearby secret army founded research
facility...

> He refers to "Arachis hypogaea", which is geek talk for peanuts.
> Get it? Arachi-donic.

Oh, we get it. Don't we?

--
Andrzej Rosa
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Tom Anderson

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Since: May 02, 2006
Posts: 298



(Msg. 14) Posted: Wed Jul 23, 2008 12:56 pm
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On Tue, 22 Jul 2008, Taka wrote:

> On Jul 22, 10:07 pm, Taka wrote:
>> On Jul 22, 8:25 pm, Tom Anderson wrote:
>>
>>> On Sat, 19 Jul 2008, Taka wrote:
>>>> The newest muscle booster is called "HemodrauliX" utilizing PGE2 to
>>>> stimulate nitric oxide synthase while supplementing it with enough
>>>> substrate in the form of Arginine. [...] How in the heck to did you do
>>>> this? You might ask. The answer is the addition of a compound called
>>>> Arachidonic Acid (AA).
>>>
>>> That's in peanuts, right?
>>
>> No, only its precursor linoleic acid. It is in relatively high
>> amounts in organ meat such as hearts and egg yolks. Also in recently
>> mentioned farmed salmon fed grains.
>
> Don't mistake arachidonic for arachidic, the latter is a saturated
> fatty acid indeed found in peanut oil:

Aaah, that explains it. Cheers.

tom

--
We can only see a short distance ahead, but we can see plenty there that
needs to be done. -- Alan Turing
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DZ

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Since: Jul 23, 2008
Posts: 1



(Msg. 15) Posted: Wed Jul 23, 2008 3:17 pm
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