Watch The Fat Melt Away

This thread died awhile ago because of lack of interest ..
Seems it shouldn't ..

http://groups.google.com/group/sci.med.nutrition/msg/35efd26a43652811

WHY would they use topical phosphatidylcholine .. ?

JOURNAL OF COSMETIC AND LASER THERAPY : OFFICIAL PUBLICATION OF THE
EUROPEAN SOCIETY FOR LASER DERMATOLOGY Vol. 9 Issue 2 Jun 2007
The effectiveness and safety of topical PhotoActif phosphatidylcholine-
based anti-cellulite gel and LED (red and near-infrared) light on
Grade II-III thigh cellulite: a randomized, double-blinded study.
Authors:

Sasaki, Gordon H
Oberg, Kerby
Tucker, Barbara
Gaston, Margaret


Affiliation: Sasaki Advanced Aesthetic Medical Center, Pasadena, CA
91105, USA. jobanna.DeleteThis@earthlink.net

Abstract:
BACKGROUND:
Cellulite of the upper lateral and posterior thighs and lower buttocks
represents a common, physiological and unwanted condition whose
etiologies and effective management are subjects of continued debate.
OBJECTIVE:
The purpose of this controlled, double-blinded study is to evaluate
the efficacy and safety of a novel phosphatidylcholine-based,
cosmeceutical anti-cellulite gel combined with a light-emitting diode
(LED) array at the wavelengths of red (660 nm) and near-infrared (950
nm), designed to counter the possible mechanisms that purportedly
accentuate the presence of thigh cellulite.
METHODS:
Nine healthy female volunteers with Grade II-III thigh cellulite were
randomly treated twice daily with an active gel on one thigh and a
placebo gel on the control thigh for 3 months. Twice weekly, each
thigh was exposed for a 15-minute treatment with LED light for a total
of 24 treatments. At 0, 6, and 12 weeks of the study the following
clinical determinants were obtained: standardized digital photography,
height and weight measurements, standardized thigh circumference tape
measurements, pinch testing, body mass index (kg/m2), body fat
analysis (Futrex-5500/XL near-infrared analyzer), and digital high-
resolution ultrasound imaging of the dermal-adiposal border. In
selected patients, full-thickness biopsies of the placebo and active-
treated sites were obtained. At 18 months, repeat standardized digital
photography, height and weight measurements, and body mass index
measurements were obtained.
RESULTS:
At the end of 3 months, eight of nine thighs treated with the
phosphatidylcholine-based, anti-cellulite gel and LED treatments were
downgraded to a lower cellulite grade by clinical examination, digital
photography, and pinch test assessment. Digital ultrasound at the
dermal-adiposal interface demonstrated not only a statistically
significant reduction of immediate hypodermal depth, but also less
echo-like intrusions into the dermal layer. Three of six biopsies from
thighs treated for 3 months with the active gel and LED treatments
demonstrated less intrusion of subcutaneous fat into the papillary and
reticular dermis. In nine placebo and LED-treated thighs and one of
the actively treated thighs, minimal clinical changes were observed or
measured by the clinical determinants throughout the 3-month study. At
the month-18 evaluation period for the eight responsive thighs, five
thighs reverted back to their original cellulite grading, while three
thighs continued to maintain their improved status. Patients
experienced minimal and transient side effects that included puritus,
erythema and swelling.
CONCLUSIONS:
The results of this small but well-documented, randomized, double-
blinded study affirms that eight of nine thighs with Grade II-III
cellulite responded positively to a novel, combined 3-month treatment
program of a phosphatidylcholine-based, anti-cellulite gel and LED
exposure, as determined by the clinical determinants obtained.
Patients experienced minimal and transient side effects. At the
month-18 evaluation period (15 months after treatment), five
responsive thighs reverted back to their original cellulite grading,
indicating a need for maintenance treatment. Future studies are needed
to verify these tentative positive observations.}

PreMedline Identifier (PMID): 17558758


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