MUSCLE IMPLANTS!!!!

In article ,
Prisoner at War wrote:

> The Beep reported on Thursday that scientists have been making muscle
> in the lab, which they then implant into rats with great results!
> Human trials are scheduled soon....
>
> They do it by mixing some muscle cells with a very thin film of some
> sort...they're not doing skeletal muscles, but smooth muscles such as
> what make up the heart and other organs -- but can skeletal muscles be
> far behind??
>
> WOW!!! Imagine, finally -- just replace that ageing biceps with new
> ones!!!

Or growing cuter ears:

http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a bitch" -- Jack Nicholson
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

Say, how do you work this google thingamajig, anyway...couldn't pull
up anything using the search terms "bbc muscle film rats implants
new"....

And didn't somebody else grow chicken meat in the lab or something
last year???


On Sep 7, 9:27 am, Omelet wrote:
> In article ,
>
>
> Or growing cuter ears:
>
> http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html
> --
> Peace, Om
>
> Remove _ to validate e-mails.
>
> "My mother never saw the irony in calling me a Son of a bitch" -- Jack Nicholson
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Sep 7, 6:49 am, Tom Anderson wrote:
>
>
> The heart isn't smooth muscle.

You're right -- I didn't mean to mention them in the same breath like
that; thanks for the correction.

> Smooth muscle is what wraps your blood
> vessels, gut, bladder, etc - it generates long, slow contractions to
> maintain static pressure. If your heart was smooth muscle, it'd beat about
> once every ten seconds.

Hmm! Is the brain smooth muscle? No, seriously!

> The heart is cardiac muscle - something different to both smooth and
> skeletal muscle, but much more similar to skeletal than smooth, in terms
> of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
> more similar to contractile non-muscle cells than they are to the other
> muscle cells in those respects; the isoforms of myosin etc they use are
> also either the same as or closely related to the non-muscle isoforms.

I wonder if bugs or lobsters have the same kind of muscles inside
their exoskeletons....

> Skeletal muscle is pretty different to smooth muscle - it has a lot more
> structure, so it'll be harder to make. You can't just mix up cultured
> cells and some laminin or whatever and expect it to work. But, it's
> probably not impossible. The right goop, the right growth factors, maybe
> some sort of microstructured scaffold ...

That's the thing...the Beep reported that it did work in rats, and
that they're going to do human trials soon...I wish I could post a
link, but I heard this on the radio, and I just didn't have any luck
with the search terms "BBC muscle film implant rats"....

> Not as absurd as you might think. Adipocytes and muscles cells are close
> to each other in the family tree of cell types, so you only have to
> persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
> stem cell (currently entirely impossible) before it's good to turn into
> a muscle cell.

Heck, just find out what biochemical signals causes fat burning,
explore any safety issues involved....

> But then you get muscles forming in some pretty weird places. Subcutaneous
> fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
> a way to make the stem cells move to the right place - like a metastasing
> cancer cell. Sounds great! And they'd have to move quite some distance,
> otherwise i'm going to have the most muscular arse this side of one of
> Pete's wet dreams, and abs bigger than my pecs.

Whatever happened to that electrostimulation stuff? Did it not work,
or not work very well, or had serious side-effects?

> tom
>
> --
> power to the people and the beats
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

In article ,
Prisoner at War wrote:

> On Sep 7, 9:27 am, Omelet wrote:
> > In article ,
> >
> >
> > Or growing cuter ears:
> >
> > http://www.madsci.org/posts/archives/2003-12/1070561342.Gb.r.html
>
> Say, how do you work this google thingamajig, anyway...couldn't pull
> up anything using the search terms "bbc muscle film rats implants
> new"....
>
> And didn't somebody else grow chicken meat in the lab or something
> last year???
>
>

It's all in the key words... I already knew about them trying to grow
noses and ears on the backs of mice and rats for plastic surgery, so I
just typed in "ear growing on a rats back" for my google search.

If one search chain does not work, try something a bit different.

Sometimes it takes some patience to find what you want. There are
literally billions of websites.

Besides, my reply to you was meant to be funny.
Perhaps you need to transplant a sense of humor.

In all seriousness, I doubt that "Muscle implants" will be useful for
body building any time soon. They are more applicable to people that
have been in serious accidents and need re-building.

On the up-side, prosthetic muscle implants have been available for years
for physique enhancement. Please note that they won't make you stronger,
just "prettier". <G>

Try here to start:

http://www.onlinesurgery.com/plasticsurgery/calf-implants.asp

There is a side bar with other procedures.
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a bitch" -- Jack Nicholson
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Fri, 7 Sep 2007, chatnoir wrote:

> Prisoner at War wrote:
>
>> The Beep reported on Thursday that scientists have been making muscle
>> in the lab, which they then implant into rats with great results! Human
>> trials are scheduled soon....
>>
>> They do it by mixing some muscle cells with a very thin film of some
>> sort...they're not doing skeletal muscles, but smooth muscles such as
>> what make up the heart and other organs

The heart isn't smooth muscle. Smooth muscle is what wraps your blood
vessels, gut, bladder, etc - it generates long, slow contractions to
maintain static pressure. If your heart was smooth muscle, it'd beat about
once every ten seconds.

The heart is cardiac muscle - something different to both smooth and
skeletal muscle, but much more similar to skeletal than smooth, in terms
of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
more similar to contractile non-muscle cells than they are to the other
muscle cells in those respects; the isoforms of myosin etc they use are
also either the same as or closely related to the non-muscle isoforms.

>> -- but can skeletal muscles be far behind??

Skeletal muscle is pretty different to smooth muscle - it has a lot more
structure, so it'll be harder to make. You can't just mix up cultured
cells and some laminin or whatever and expect it to work. But, it's
probably not impossible. The right goop, the right growth factors, maybe
some sort of microstructured scaffold ...

>> WOW!!! Imagine, finally -- just replace that ageing biceps with new
>> ones!!!
>
> America needs a process that turns fat into muscle tissue!

Not as absurd as you might think. Adipocytes and muscles cells are close
to each other in the family tree of cell types, so you only have to
persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
stem cell (currently entirely impossible) before it's good to turn into
a muscle cell.

But then you get muscles forming in some pretty weird places. Subcutaneous
fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
a way to make the stem cells move to the right place - like a metastasing
cancer cell. Sounds great! And they'd have to move quite some distance,
otherwise i'm going to have the most muscular arse this side of one of
Pete's wet dreams, and abs bigger than my pecs.

tom

--
power to the people and the beats
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

Tom Anderson wrote in


> On Fri, 7 Sep 2007, chatnoir wrote:
>
>> Prisoner at War wrote:
>>
>>> The Beep reported on Thursday that scientists have been making
>>> muscle in the lab, which they then implant into rats with great
>>> results! Human trials are scheduled soon....
>>>
>>> They do it by mixing some muscle cells with a very thin film of some
>>> sort...they're not doing skeletal muscles, but smooth muscles such
>>> as what make up the heart and other organs
>
> The heart isn't smooth muscle. Smooth muscle is what wraps your blood
> vessels, gut, bladder, etc - it generates long, slow contractions to
> maintain static pressure. If your heart was smooth muscle, it'd beat
> about once every ten seconds.
>
> The heart is cardiac muscle - something different to both smooth and
> skeletal muscle, but much more similar to skeletal than smooth, in
> terms of ultrastructure, regulation, etc. Smooth muscle cells are
> actually a lot more similar to contractile non-muscle cells than they
> are to the other muscle cells in those respects; the isoforms of
> myosin etc they use are also either the same as or closely related to
> the non-muscle isoforms.
>
>>> -- but can skeletal muscles be far behind??
>
> Skeletal muscle is pretty different to smooth muscle - it has a lot
> more structure, so it'll be harder to make. You can't just mix up
> cultured cells and some laminin or whatever and expect it to work.
> But, it's probably not impossible. The right goop, the right growth
> factors, maybe some sort of microstructured scaffold ...
>
>>> WOW!!! Imagine, finally -- just replace that ageing biceps with new
>>> ones!!!
>>
>> America needs a process that turns fat into muscle tissue!
>
> Not as absurd as you might think. Adipocytes and muscles cells are
> close to each other in the family tree of cell types, so you only have
> to persuade a fat cell to dedifferentiate a few steps back to a
> mesenchymal stem cell (currently entirely impossible) before it's good
> to turn into a muscle cell.
>
> But then you get muscles forming in some pretty weird places.
> Subcutaneous fat becoming subcutaneous muscle? Er, no thanks. Unless
> you can figure out a way to make the stem cells move to the right
> place - like a metastasing cancer cell. Sounds great! And they'd have
> to move quite some distance, otherwise i'm going to have the most
> muscular arse this side of one of Pete's wet dreams, and abs bigger
> than my pecs.
>
> tom


Man, I wish I'd have had some muscle implants before I made my flexing
video. I would have looked so hot. I would have rubbed myself down
with baby oil and worn a speeo.

I'm now thinking of getting a butt lift, for the next time I take
pictures of my own butt, I'd have something to be REALLY proud of.

Thanks for the news

--
Bill Davidson

I removed the picture of my butt from the website, because I
wanted to take some better ones, maybe with me inserting
some toys. For now, here are pictures I took while stalking
sunbathers here:

http://s88.photobucket.com/albums/k170/bagpip1/Beach/
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Fri, 7 Sep 2007, Prisoner at War wrote:

> On Sep 7, 6:49 am, Tom Anderson wrote:
>
>> Smooth muscle is what wraps your blood vessels, gut, bladder, etc - it
>> generates long, slow contractions to maintain static pressure. If your
>> heart was smooth muscle, it'd beat about once every ten seconds.
>
> Hmm! Is the brain smooth muscle? No, seriously!

No.

>> The heart is cardiac muscle - something different to both smooth and
>> skeletal muscle, but much more similar to skeletal than smooth, in
>> terms of ultrastructure, regulation, etc. Smooth muscle cells are
>> actually a lot more similar to contractile non-muscle cells than they
>> are to the other muscle cells in those respects; the isoforms of myosin
>> etc they use are also either the same as or closely related to the
>> non-muscle isoforms.
>
> I wonder if bugs or lobsters have the same kind of muscles inside their
> exoskeletons....

They do.

The simplest animals don't - jellyfish only have smooth muscle, and some
sort of hybrid epithelial-muscle cell (epithelial cells being what makes
up your skin, the lining of your gut, etc). I have no idea where in the
tree of life skeletal muscle evolved.

>> Skeletal muscle is pretty different to smooth muscle - it has a lot
>> more structure, so it'll be harder to make. You can't just mix up
>> cultured cells and some laminin or whatever and expect it to work. But,
>> it's probably not impossible. The right goop, the right growth factors,
>> maybe some sort of microstructured scaffold ...
>
> That's the thing...the Beep reported that it did work in rats, and that
> they're going to do human trials soon...I wish I could post a link, but
> I heard this on the radio, and I just didn't have any luck with the
> search terms "BBC muscle film implant rats"....

Me neither.

>> Not as absurd as you might think. Adipocytes and muscles cells are
>> close to each other in the family tree of cell types, so you only have
>> to persuade a fat cell to dedifferentiate a few steps back to a
>> mesenchymal stem cell (currently entirely impossible) before it's good
>> to turn into a muscle cell.
>
> Heck, just find out what biochemical signals causes fat burning,
> explore any safety issues involved....

Dinitrophenol, plus plenty of water, vitamin C and air conditioning.

tom

--
I burning your dog.
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

In article ,
Tom Anderson wrote:

> > Heck, just find out what biochemical signals causes fat burning,
> > explore any safety issues involved....
>
> Dinitrophenol, plus plenty of water, vitamin C and air conditioning.
>
> tom

Nice one.
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a bitch" -- Jack Nicholson
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Sep 7, 2:22 pm, Prisoner at War wrote:
[...]

> Are you and Curt big time Scrabble players or something??

Using all seven tiles during one turn is a thing of beauty. And an
extra fifty points! ;o)

--
Curt
Bonus trivia: QAT is defined as the leaves of the shrub Catha edulis
which are chewed like tobacco or used to make tea; has the effect of a
euphoric stimulant.
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Sep 7, 2:49 pm, Omelet wrote:
[...]

> Ask Curt to try. He's better at it than I am.

Flattery will get you everywhere. What's your address again? Ammo in
your mailbox! Uh...

Dear FBI/BATF:

i KEED! i KEED!

Regards,
NOT Curt

[...]

> <lol> Humor makes life worth living.

Undoubtedly.

re http://www.onlinesurgery.com/plasticsurgery/calf-implants.asp

[...]

> If nobody used them, they'd not spend the money making, or advertise
> them.

Definitely. Disfiguring accidents were mentioned. And simple self
esteem would not be an unreasonable justification, imo.

--
Curt
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

On Sep 7, 4:49 am, Tom Anderson wrote:
> On Fri, 7 Sep 2007, chatnoir wrote:
> > Prisoner at War wrote:
>
> >> The Beep reported on Thursday that scientists have been making muscle
> >> in the lab, which they then implant into rats with great results! Human
> >> trials are scheduled soon....
>
> >> They do it by mixing some muscle cells with a very thin film of some
> >> sort...they're not doing skeletal muscles, but smooth muscles such as
> >> what make up the heart and other organs
>
> The heart isn't smooth muscle. Smooth muscle is what wraps your blood
> vessels, gut, bladder, etc - it generates long, slow contractions to
> maintain static pressure. If your heart was smooth muscle, it'd beat about
> once every ten seconds.
>
> The heart is cardiac muscle - something different to both smooth and
> skeletal muscle, but much more similar to skeletal than smooth, in terms
> of ultrastructure, regulation, etc. Smooth muscle cells are actually a lot
> more similar to contractile non-muscle cells than they are to the other
> muscle cells in those respects; the isoforms of myosin etc they use are
> also either the same as or closely related to the non-muscle isoforms.
>
> >> -- but can skeletal muscles be far behind??
>
> Skeletal muscle is pretty different to smooth muscle - it has a lot more
> structure, so it'll be harder to make. You can't just mix up cultured
> cells and some laminin or whatever and expect it to work. But, it's
> probably not impossible. The right goop, the right growth factors, maybe
> some sort of microstructured scaffold ...
>
> >> WOW!!! Imagine, finally -- just replace that ageing biceps with new
> >> ones!!!
>
> > America needs a process that turns fat into muscle tissue!
>
> Not as absurd as you might think. Adipocytes and muscles cells are close
> to each other in the family tree of cell types, so you only have to
> persuade a fat cell to dedifferentiate a few steps back to a mesenchymal
> stem cell (currently entirely impossible) before it's good to turn into
> a muscle cell.
>
> But then you get muscles forming in some pretty weird places. Subcutaneous
> fat becoming subcutaneous muscle? Er, no thanks. Unless you can figure out
> a way to make the stem cells move to the right place - like a metastasing
> cancer cell. Sounds great! And they'd have to move quite some distance,
> otherwise i'm going to have the most muscular arse this side of one of
> Pete's wet dreams, and abs bigger than my pecs.
>
> tom


Beats Diabetes
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

Prisoner at War wrote:
> The Beep reported on Thursday that scientists have been making muscle
> in the lab, which they then implant into rats with great results!
> Human trials are scheduled soon....
>
> They do it by mixing some muscle cells with a very thin film of some
> sort...they're not doing skeletal muscles, but smooth muscles such as
> what make up the heart and other organs -- but can skeletal muscles be
> far behind??
>
> WOW!!! Imagine, finally -- just replace that ageing biceps with new
> ones!!!
>
It may be of help to people who already have functioning muscles and
just want to build them up again, but it doesn't offer hope for those
who have permanent paralysis in that muscle..it won't help to replace
the muscle as it too would just atrophy without being hooked up to the
central nervous system.
this is just my opinion as one who lives with paralysis.
 >> Stay informed about: MUSCLE IMPLANTS!!!! 

In article ,
Curt wrote:

> On Sep 7, 2:22 pm, Prisoner at War wrote:
> [...]
>
> > Are you and Curt big time Scrabble players or something??
>
> Using all seven tiles during one turn is a thing of beauty. And an
> extra fifty points! ;o)
>
> --
> Curt
> Bonus trivia: QAT is defined as the leaves of the shrub Catha edulis
> which are chewed like tobacco or used to make tea; has the effect of a
> euphoric stimulant.

Ooh I did not know that it was worth an extra score!
I'll have to try a little harder next time.

The only game I love more than Scrabble is Boggle.
--
Peace, Om

Remove _ to validate e-mails.

"My mother never saw the irony in calling me a Son of a bitch" -- Jack Nicholson
 >> Stay informed about: MUSCLE IMPLANTS!!!!